The Red Sox Foundation and Massachusetts General Hospital Home Base Program is seeking participants for a major national study. This study is funded by the Department of Defense, and will explore treatments for Post Traumatic Stress Disorder (PTSD).
What is Post Traumatic Stress Disorder? PTSD can develop following exposure to a traumatic event, such as military combat. Individuals with PTSD often experience:
• Irritability and rage
• Feelings of numbness and avoidance
• Feelings of disconnection from family or friends
• Trouble concentrating
• Jumpiness or feelings of being on edge
• Flashbacks or nightmares related to the trauma
What will the study do? The study will compare the effectiveness of the following for treatment of PTSD.
• the medication sertraline
• prolonged exposure therapy (a type of talk therapy)
• sertraline plus prolonged exposure therapy
How long is the study? Up to six months with follow up assessments at twelve months.
Would I be paid for participating? Yes. If you qualify to participate, you will be paid $50 for each of the six assessments you complete, for a maximum total of $300. You will be paid by a check that will be issued approximately three weeks after completing each assessment.
Are sertraline and prolonged exposure therapy safe? Sertraline is approved by the U.S. Food and Drug Administration (FDA) for the treatment of PTSD. Both sertraline and prolonged exposure therapy have been shown to be effective in treating PTSD.
What happens if I decide to participate? You will start with a brief phone interview. Then, if the study seems like a good match for you, you will meet with a clinician who will determine if you are eligible to participate.
How will the study work? Eligible study participants will be randomly assigned to one of three study treatments:
• Prolonged Exposure Therapy + sertraline
• Prolonged Exposure Therapy + placebo (a sugar pill without active medication)
• Sertraline without Prolonged Exposure Therapy At the end of the study, all participants will be told what medication they took (sertraline or placebo) and will be eligible for behavioral health care at Home Base at no additional cost to them.
Brain Imaging Option: If you qualify for the study, you would also have the opportunity to participate in optional brain imaging scans in Michigan. If you choose to do this you will be compensated for your time and travel expenses.